Identification of an Immunogenic Medulloblastoma-Specific Fusion Involving <i>EPC2</i> and <i>GULP1</i>

Identification of an Immunogenic Medulloblastoma-Specific Fusion Involving <i>EPC2</i> and <i>GULP1</i>

Medulloblastoma is the most common malignant brain tumor in children. Immunotherapy is yet to demonstrate dramatic results in medulloblastoma, one reason being the low rate of mutations creating new antigens in this entity. In tumors with low mutational burden, gene fusions may represent a source of...

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Autores principales: Claudia Paret, Nadine Lehmann, Hannah Bender, Maximilian Sprang, Clemens J. Sommer, Denis Cana, Larissa Seidmann, Arthur Wingerter, Marie A. Neu, Khalifa El Malki, Francesca Alt, Lea Roth, Federico Marini, Malte Ottenhausen, Martin Glaser, Markus Knuf, Alexandra Russo, Joerg Faber
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
medulloblastoma
EPC2
GULP1
fusion
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Acceso en línea:https://doaj.org/article/ef2a8eb1cda543319a2d2d59080d5609
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https://doaj.org/article/ef2a8eb1cda543319a2d2d59080d5609

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