Super-complexes of adhesion GPCRs and neural guidance receptors

Super-complexes of adhesion GPCRs and neural guidance receptors

FLRT proteins are known to interact with Lphns and Unc5s, mediating cell adhesion and repulsion respectively. Here the authors use crystallography, native mass spectrometry, molecular dynamics simulations and cell-based assays to show that these three proteins form large super-complexes with functio...

Full description

Saved in:
Bibliographic Details
Main Authors: Verity A. Jackson, Shahid Mehmood, Matthieu Chavent, Pietro Roversi, Maria Carrasquero, Daniel del Toro, Goenuel Seyit-Bremer, Fanomezana M. Ranaivoson, Davide Comoletti, Mark S. P. Sansom, Carol V. Robinson, Rüdiger Klein, Elena Seiradake
Format: article
Language:EN
Published: Nature Portfolio 2016
Subjects:
Science
Q
Online Access:https://doaj.org/article/ef384409442e4b9a8531b5fb0fc42da1
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/ef384409442e4b9a8531b5fb0fc42da1

Similar Items