Convergent evolution of a genomic rearrangement may explain cancer resistance in hystrico- and sciuromorpha rodents
Abstract The rodents of hystricomorpha and sciuromorpha suborders exhibit remarkably lower incidence of cancer. The underlying genetic basis remains obscure. We report a convergent evolutionary split of human 3p21.31, a locus hosting a large number of tumour-suppressor genes (TSGs) and frequently de...
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Auteurs principaux: | , , , , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2021
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Accès en ligne: | https://doaj.org/article/ef48398f433c4d418e7292a983c20452 |
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