Predicted Epitope Abundance Supports Vaccine-Induced Cytotoxic Protection Against SARS-CoV-2 Variants of Concern

The effect of emerging SARS-CoV-2 variants on vaccine efficacy is of critical importance. In this study, the potential impact of mutations that facilitate escape from the cytotoxic cellular immune response in these new virus variants for the 551 most abundant HLA class I alleles was analyzed. Comput...

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Autores principales: Antonio J. Martín-Galiano, Francisco Díez-Fuertes, Michael J. McConnell, Daniel López
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
HLA
Acceso en línea:https://doaj.org/article/ef97a7e4b38a45e0b1cc6dfde71859aa
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