SIRT1 Promotes M2 Microglia Polarization via Reducing ROS-Mediated NLRP3 Inflammasome Signaling After Subarachnoid Hemorrhage

Mounting evidence has suggested that modulating microglia polarization from pro-inflammatory M1 phenotype to anti-inflammatory M2 state might be a potential therapeutic approach in the treatment of subarachnoid hemorrhage (SAH) injury. Our previous study has indicated that sirtuin 1 (SIRT1) could am...

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Autores principales: Da-Yong Xia, Jin-Long Yuan, Xiao-Chun Jiang, Min Qi, Nian-Sheng Lai, Ling-Yun Wu, Xiang-Sheng Zhang
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/efa1ff860b80456184819e75f052903e
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