Two Pathways of p27<sup>Kip1</sup> Degradation Are Required for Murine Lymphoma Driven by Myc and EBV Latent Membrane Protein 2A
ABSTRACT Epstein-Barr virus (EBV) latent membrane protein 2A (LMP2A), expressed in EBV latency, contributes to Burkitt lymphoma (BL) development in a murine model by acting as a constitutively active B cell receptor (BCR) mimic. Mice expressing both LMP2A and MYC transgenes (LMP2A/λ-MYC) develop tum...
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| Auteurs principaux: | , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
American Society for Microbiology
2019
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| Accès en ligne: | https://doaj.org/article/efb903ff4448408aa638abfe735e43b4 |
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