CRISPR-Cas9 targeted disruption of the yellow ortholog in the housefly identifies the brown body locus

Abstract The classic brown body (bwb) mutation in the housefly Musca domestica impairs normal melanization of the adult cuticle. In Drosophila melanogaster, a reminiscent pigmentation defect results from mutations in the yellow gene encoding dopachrome conversion enzyme (DCE). Here, we demonstrate t...

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Autores principales: Svenia D. Heinze, Tea Kohlbrenner, Domenica Ippolito, Angela Meccariello, Alexa Burger, Christian Mosimann, Giuseppe Saccone, Daniel Bopp
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/efc5dcc9906c4412afaf3bf225ef5ea1
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