Synthesis of chiral anti-1,2-diamine derivatives through copper(I)-catalyzed asymmetric α-addition of ketimines to aldimines

Chiral 1,2-diamines are useful chemicals used as ligands in asymmetric catalysis. Here, the authors report a copper(I)-catalyzed asymmetric α-addition of ketimines derived from trifluoroacetophenone and 2- or 4-NO2-benzylamines to aldimines, affording a series of chiral anti-1,2-diamine derivatives....

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Autores principales: Xu-Cheng Gan, Cheng-Yuan Zhang, Feng Zhong, Ping Tian, Liang Yin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/eff4966fcbdc48778f180a41183504ce
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