Synthesis of chiral anti-1,2-diamine derivatives through copper(I)-catalyzed asymmetric α-addition of ketimines to aldimines

Chiral 1,2-diamines are useful chemicals used as ligands in asymmetric catalysis. Here, the authors report a copper(I)-catalyzed asymmetric α-addition of ketimines derived from trifluoroacetophenone and 2- or 4-NO2-benzylamines to aldimines, affording a series of chiral anti-1,2-diamine derivatives....

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Xu-Cheng Gan, Cheng-Yuan Zhang, Feng Zhong, Ping Tian, Liang Yin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/eff4966fcbdc48778f180a41183504ce
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:eff4966fcbdc48778f180a41183504ce
record_format	dspace
spelling	oai:doaj.org-article:eff4966fcbdc48778f180a41183504ce2021-12-02T17:19:42ZSynthesis of chiral anti-1,2-diamine derivatives through copper(I)-catalyzed asymmetric α-addition of ketimines to aldimines10.1038/s41467-020-18235-92041-1723https://doaj.org/article/eff4966fcbdc48778f180a41183504ce2020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18235-9https://doaj.org/toc/2041-1723Chiral 1,2-diamines are useful chemicals used as ligands in asymmetric catalysis. Here, the authors report a copper(I)-catalyzed asymmetric α-addition of ketimines derived from trifluoroacetophenone and 2- or 4-NO2-benzylamines to aldimines, affording a series of chiral anti-1,2-diamine derivatives.Xu-Cheng GanCheng-Yuan ZhangFeng ZhongPing TianLiang YinNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xu-Cheng Gan Cheng-Yuan Zhang Feng Zhong Ping Tian Liang Yin Synthesis of chiral anti-1,2-diamine derivatives through copper(I)-catalyzed asymmetric α-addition of ketimines to aldimines
description	Chiral 1,2-diamines are useful chemicals used as ligands in asymmetric catalysis. Here, the authors report a copper(I)-catalyzed asymmetric α-addition of ketimines derived from trifluoroacetophenone and 2- or 4-NO2-benzylamines to aldimines, affording a series of chiral anti-1,2-diamine derivatives.
format	article
author	Xu-Cheng Gan Cheng-Yuan Zhang Feng Zhong Ping Tian Liang Yin
author_facet	Xu-Cheng Gan Cheng-Yuan Zhang Feng Zhong Ping Tian Liang Yin
author_sort	Xu-Cheng Gan
title	Synthesis of chiral anti-1,2-diamine derivatives through copper(I)-catalyzed asymmetric α-addition of ketimines to aldimines
title_short	Synthesis of chiral anti-1,2-diamine derivatives through copper(I)-catalyzed asymmetric α-addition of ketimines to aldimines
title_full	Synthesis of chiral anti-1,2-diamine derivatives through copper(I)-catalyzed asymmetric α-addition of ketimines to aldimines
title_fullStr	Synthesis of chiral anti-1,2-diamine derivatives through copper(I)-catalyzed asymmetric α-addition of ketimines to aldimines
title_full_unstemmed	Synthesis of chiral anti-1,2-diamine derivatives through copper(I)-catalyzed asymmetric α-addition of ketimines to aldimines
title_sort	synthesis of chiral anti-1,2-diamine derivatives through copper(i)-catalyzed asymmetric α-addition of ketimines to aldimines
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/eff4966fcbdc48778f180a41183504ce
work_keys_str_mv	AT xuchenggan synthesisofchiralanti12diaminederivativesthroughcoppericatalyzedasymmetricaadditionofketiminestoaldimines AT chengyuanzhang synthesisofchiralanti12diaminederivativesthroughcoppericatalyzedasymmetricaadditionofketiminestoaldimines AT fengzhong synthesisofchiralanti12diaminederivativesthroughcoppericatalyzedasymmetricaadditionofketiminestoaldimines AT pingtian synthesisofchiralanti12diaminederivativesthroughcoppericatalyzedasymmetricaadditionofketiminestoaldimines AT liangyin synthesisofchiralanti12diaminederivativesthroughcoppericatalyzedasymmetricaadditionofketiminestoaldimines
_version_	1718381059093037056

Synthesis of chiral anti-1,2-diamine derivatives through copper(I)-catalyzed asymmetric α-addition of ketimines to aldimines

Ejemplares similares