The Modified Surface Killing Assay Distinguishes between Protective and Nonprotective Antibodies to PspA

ABSTRACT Pneumococcal surface protein A (PspA) elicits antibody protective against lethal challenge by Streptococcus pneumoniae and is a candidate noncapsular antigen for inclusion in vaccines. Evaluation of immunity to PspA in human trials would be greatly facilitated by an in vitro functional assa...

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Autores principales: Kristopher R. Genschmer, Cintia F. M. Vadesilho, Larry S. McDaniel, Sang-Sang Park, Yvette Hale, Eliane N. Miyaji, David E. Briles
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
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Acceso en línea:https://doaj.org/article/effb57108d0349dd800cafa469a29160
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