Profiling and Functional Analysis of microRNA Deregulation in Cancer-Associated Fibroblasts in Oral Squamous Cell Carcinoma Depicts an Anti-Invasive Role of microRNA-204 via Regulation of Their Motility

Profiling and Functional Analysis of microRNA Deregulation in Cancer-Associated Fibroblasts in Oral Squamous Cell Carcinoma Depicts an Anti-Invasive Role of microRNA-204 via Regulation of Their Motility

<i>Background:</i> Knowledge on the role of miR changes in tumor stroma for cancer progression is limited. This study aimed to investigate the role of miR dysregulation in cancer-associated fibroblasts (CAFs) in oral squamous cell carcinoma (OSCC). <i>Methodology:</i> CAF and...

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Main Authors: Saroj Rajthala, Anjie Min, Himalaya Parajuli, Kala Chand Debnath, Borghild Ljøkjel, Kristin Marie Hoven, Arild Kvalheim, Stein Lybak, Evelyn Neppelberg, Olav Karsten Vintermyr, Anne Christine Johannessen, Dipak Sapkota, Daniela Elena Costea
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
oral squamous cell carcinoma
miR-204
fibroblasts
tumor stroma
ITGA11
Biology (General)
QH301-705.5
Chemistry
QD1-999
Online Access:https://doaj.org/article/effe369824c044b091b058fc650fb079
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https://doaj.org/article/effe369824c044b091b058fc650fb079

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