Epithelial cell specific Raptor is required for initiation of type 2 mucosal immunity in small intestine

Abstract Intestinal tuft cells are one of 4 secretory cell linages in the small intestine and the source of IL-25, a critical initiator of the type 2 immune response to parasite infection. When Raptor, a critical scaffold protein for mammalian target of rapamycin complex 1 (mTORC1), was acutely dele...

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Autores principales: Bola Aladegbami, Lauren Barron, James Bao, Jason Colasanti, Christopher R. Erwin, Brad W. Warner, Jun Guo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/f002d43a0f434520a9951e5dbcbb5947
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