Quantitative analysis of receptor-mediated uptake and pro-apoptotic activity of mistletoe lectin-1 by high content imaging
Abstract Ribosome inactivating proteins (RIPs) are highly potent cytotoxins that have potential as anticancer therapeutics. Mistletoe lectin 1 (ML1) is a heterodimeric cytotoxic protein isolated from European Mistletoe and belongs to RIP class II. The aim of this project was to systematically study...
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Main Authors: | N. Beztsinna, M. B. C. de Matos, J. Walther, C. Heyder, E. Hildebrandt, G. Leneweit, E. Mastrobattista, R. J. Kok |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
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Online Access: | https://doaj.org/article/f01b05bd7dc54a97b4639ca51fc7ac36 |
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