Modular actin nano-architecture enables podosome protrusion and mechanosensing

Modular actin nano-architecture enables podosome protrusion and mechanosensing

Podosomes are actin-based protrusions used by cells for invasion and local degradation but the structure underlying their protrusiveness and mechanosensitivity is unclear. Here, the authors report that podosomes have a modular actin nano-architecture whose organization differs on stiff or soft subst...

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Autores principales: Koen van den Dries, Leila Nahidiazar, Johan A. Slotman, Marjolein B. M. Meddens, Elvis Pandzic, Ben Joosten, Marleen Ansems, Joost Schouwstra, Anke Meijer, Raymond Steen, Mietske Wijers, Jack Fransen, Adriaan B. Houtsmuller, Paul W. Wiseman, Kees Jalink, Alessandra Cambi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/f02ec8baa69243f385139e1d26c11672
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https://doaj.org/article/f02ec8baa69243f385139e1d26c11672

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