Fibronectin promotes directional persistence in fibroblast migration through interactions with both its cell-binding and heparin-binding domains
Abstract The precise mechanisms through which insoluble, cell-adhesive ligands induce and regulate directional cell migration remain obscure. We recently demonstrated that elevated surface density of physically adsorbed plasma fibronectin (FN) promotes high directional persistence in fibroblast migr...
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Main Authors: | Dimitris Missirlis, Tamás Haraszti, Horst Kessler, Joachim P. Spatz |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
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Online Access: | https://doaj.org/article/f05ac0fbbf9a498f9e9f5b297e6e308e |
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