Roles of two types of heparan sulfate clusters in Wnt distribution and signaling in Xenopus

Wnt proteins mediate embryonic development but how protein localization and patterning is regulated is unclear. Here, the authors show that distinct structures with different heparan sulfate modifications (‘N-sulfo-rich’ and ‘N-acetyl-rich’) regulate cellular localization and signal transduction of...

Full description

Saved in:
Bibliographic Details
Main Authors: Yusuke Mii, Takayoshi Yamamoto, Ritsuko Takada, Shuji Mizumoto, Makoto Matsuyama, Shuhei Yamada, Shinji Takada, Masanori Taira
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Q
Online Access:https://doaj.org/article/f0792f5891d54f889587aed241efe068
Tags: Add Tag
No Tags, Be the first to tag this record!