Mirtron-mediated RNA knockdown/replacement therapy for the treatment of dominant retinitis pigmentosa
Rhodopsin-related dominant retinitis pigmentosa is a degenerative disease of the retina of the eye for which there is no current treatment. In this study, the authors use a novel form of RNA-interference- artificial mirtrons- to slow retinal degeneration in a mouse model of the disease.
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Main Authors: | Harry O. Orlans, Michelle E. McClements, Alun R. Barnard, Cristina Martinez-Fernandez de la Camara, Robert E. MacLaren |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/f079a2227d8741e1858d4c8fe8a57b28 |
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