EGL-9 controls C. elegans host defense specificity through prolyl hydroxylation-dependent and -independent HIF-1 pathways.

Understanding host defense against microbes is key to developing new and more effective therapies for infection and inflammatory disease. However, how animals integrate multiple environmental signals and discriminate between different pathogens to mount specific and tailored responses remains poorly...

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Auteurs principaux: Lyly G Luhachack, Orane Visvikis, Amanda C Wollenberg, Adam Lacy-Hulbert, Lynda M Stuart, Javier E Irazoqui
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2012
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Accès en ligne:https://doaj.org/article/f086950cbd784a35afe744de2f788c99
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