Dendritic excitation–inhibition balance shapes cerebellar output during motor behaviour
Here, the authors combinein vivopatch-clamp recordings and optogenetics to show that balanced dendritic excitation and inhibition provides a sensitive ‘push-pull’ mechanism that generates the bidirectional modulation of Purkinje cell SSp output necessary for normal locomotor behaviour.
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Main Authors: | Marta Jelitai, Paolo Puggioni, Taro Ishikawa, Arianna Rinaldi, Ian Duguid |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2016
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Subjects: | |
Online Access: | https://doaj.org/article/f0a67b918c38454580d5502fe31af9b8 |
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