Distinct ubiquitin binding modes exhibited by SH3 domains: molecular determinants and functional implications.

SH3 domains constitute a new type of ubiquitin-binding domains. We previously showed that the third SH3 domain (SH3-C) of CD2AP binds ubiquitin in an alternative orientation. We have determined the structure of the complex between first CD2AP SH3 domain and ubiquitin and performed a structural and m...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Jose L Ortega Roldan, Salvador Casares, Malene Ringkjøbing Jensen, Nayra Cárdenes, Jerónimo Bravo, Martin Blackledge, Ana I Azuaga, Nico A J van Nuland
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/f0dfce6381094a71b4f4d8cd64cd8eef
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!