Loss of Parkinson’s disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c
Mutations inCHCHD2 are associated with Parkinson’s disease. Here the authors investigate the physiological and pathological roles of CHCHD2 in Drosophilaand mammalian cells, and find that it regulates mitochondrial respiration through stabilizing cytochrome c.
Guardado en:
| Autores principales: | , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2017
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/f0f13ae34fb3421384e2c167bf51757f |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| Sumario: | Mutations inCHCHD2 are associated with Parkinson’s disease. Here the authors investigate the physiological and pathological roles of CHCHD2 in Drosophilaand mammalian cells, and find that it regulates mitochondrial respiration through stabilizing cytochrome c. |
|---|