Role of epithelial to mesenchymal transition associated genes in mammary gland regeneration and breast tumorigenesis

Role of epithelial to mesenchymal transition associated genes in mammary gland regeneration and breast tumorigenesis

The contribution of EMT in mammary gland homeostasis and human breast cancer is still unclear. Here, using in vivo lineage tracing and breast cancer PDXs the authors demonstrate that the repopulating capacity in normal mammary epithelial cells and tumorigenic capacity in breast cancer is independent...

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Autores principales: Shaheen S. Sikandar, Angera H. Kuo, Tomer Kalisky, Shang Cai, Maider Zabala, Robert W. Hsieh, Neethan A. Lobo, Ferenc A. Scheeren, Sopheak Sim, Dalong Qian, Frederick M. Dirbas, George Somlo, Stephen R. Quake, Michael F. Clarke
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Science
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Acceso en línea:https://doaj.org/article/f0f50f3b3e2d42029e585ebb81c7168c
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https://doaj.org/article/f0f50f3b3e2d42029e585ebb81c7168c

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