Safe and effective aerosolization of in vitro transcribed mRNA to the respiratory tract epithelium of horses without a transfection agent
Abstract Vaccines and therapeutics using in vitro transcribed mRNA hold enormous potential for human and veterinary medicine. Transfection agents are widely considered to be necessary to protect mRNA and enhance transfection, but they add expense and raise concerns regarding quality control and safe...
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Autores principales: | Rebecca M. Legere, Noah D. Cohen, Cristina Poveda, Jocelyne M. Bray, Rola Barhoumi, Joseph A. Szule, Andrés de la Concha-Bermejillo, Angela I. Bordin, Jeroen Pollet |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/f0fc16a29af14728a68a1da1325adeb2 |
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