Ciliary Hedgehog signaling regulates cell survival to build the facial midline
Craniofacial defects are among the most common phenotypes caused by ciliopathies, yet the developmental and molecular etiology of these defects is poorly understood. We investigated multiple mouse models of human ciliopathies (including Tctn2, Cc2d2a, and Tmem231 mutants) and discovered that each di...
Saved in:
Main Authors: | Shaun R Abrams, Jeremy F Reiter |
---|---|
Format: | article |
Language: | EN |
Published: |
eLife Sciences Publications Ltd
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/f11836e51aab41898f41c1a9efe6035c |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Insights into the Regulation of Ciliary Disassembly
by: Maulin M. Patel, et al.
Published: (2021) -
SAG therapy restores bone growth and reduces enchondroma incidence in a model of skeletal chondrodysplasias caused by Ihh deficiency
by: Xinhua Li, et al.
Published: (2021) -
Wnt1 Lineage Specific Deletion of Gpr161 Results in Embryonic Midbrain Malformation and Failure of Craniofacial Skeletal Development
by: Sung-Eun Kim, et al.
Published: (2021) -
Inmunolocalización de Sonic Hedgehog en el Desarrollo Embrio-Fetal de Ratones ( Mus musculus )
by: Conei,Daniel, et al.
Published: (2018) -
Effect of kaempferol on hedgehog signaling pathway in rats with ‐‐chronic atrophic gastritis – Based on network pharmacological screening and experimental verification
by: Wenling Tu, et al.
Published: (2022)