Ciliary Hedgehog signaling regulates cell survival to build the facial midline

Craniofacial defects are among the most common phenotypes caused by ciliopathies, yet the developmental and molecular etiology of these defects is poorly understood. We investigated multiple mouse models of human ciliopathies (including Tctn2, Cc2d2a, and Tmem231 mutants) and discovered that each di...

Full description

Saved in:
Bibliographic Details
Main Authors: Shaun R Abrams, Jeremy F Reiter
Format: article
Language:EN
Published: eLife Sciences Publications Ltd 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/f11836e51aab41898f41c1a9efe6035c
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items