Power determination in vitamin D randomised control trials and characterising factors affecting it through a novel simulation-based tool

Abstract Thousands of observational studies have linked vitamin D deficiency with numerous diseases, but randomised controlled trials (RCTs) often fail to show benefit of supplementation. Population characteristics and trial design have long been suspected to undermine power but were not systematica...

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Détails bibliographiques
Auteurs principaux: Jason Wyse, Rebecca Mangan, Lina Zgaga
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/f1447639aae740ffbcac08cbd92a0e33
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