A proteomic view at T cell costimulation.

The "two-signal paradigm" in T cell activation predicts that the cooperation of "signal 1," provided by the T cell receptor (TCR) through engagement of major histocompatility complex (MHC)-presented peptide, with "signal 2″ provided by costimulatory molecules, the prototype...

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Autores principales: Rudolf Lichtenfels, Gunter Rappl, Andreas A Hombach, Christian V Recktenwald, Sven P Dressler, Hinrich Abken, Barbara Seliger
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/f15381e356fe4abd9692c874411232ca
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