Cilia locally synthesize proteins to sustain their ultrastructure and functions
Cilia are microtubule-based organelles containing proteins transported from the cell body. Here, the authors show that the multicilia of mouse ependymal cells contain ribosomal components, tubulin mRNA,18 S rRNA and nascent tubulin peptides, suggesting local translation in the ciliary compartment.
Saved in:
Main Authors: | Kai Hao, Yawen Chen, Xiumin Yan, Xueliang Zhu |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/f153ef30b907416d8975a2a3bce6b9d5 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The BEACH Protein LRBA Promotes the Localization of the Heterotrimeric G-protein Golf to Olfactory Cilia
by: Stefan Kurtenbach, et al.
Published: (2017) -
TALPID3 and ANKRD26 selectively orchestrate FBF1 localization and cilia gating
by: Hao Yan, et al.
Published: (2020) -
Mutations in radial spoke head genes and ultrastructural cilia defects in East-European cohort of primary ciliary dyskinesia patients.
by: Ewa Ziętkiewicz, et al.
Published: (2012) -
ACE2 localizes to the respiratory cilia and is not increased by ACE inhibitors or ARBs
by: Ivan T. Lee, et al.
Published: (2020) -
The localization of amyloid precursor protein to ependymal cilia in vertebrates and its role in ciliogenesis and brain development in zebrafish
by: Jasmine Chebli, et al.
Published: (2021)