Control of tissue growth and cell transformation by the Salvador/Warts/Hippo pathway.

The Salvador-Warts-Hippo (SWH) pathway is an important regulator of tissue growth that is frequently subverted in human cancer. The key oncoprotein of the SWH pathway is the transcriptional co-activator, Yes-associated protein (YAP). YAP promotes tissue growth and transformation of cultured cells by...

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Autores principales: Xiaomeng Zhang, Felix A Grusche, Kieran F Harvey
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/f1952c83599a40a59730544435d57999
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