Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication.

Reciprocal interactions between neurons and oligodendrocytes are not only crucial for myelination, but also for long-term survival of axons. Degeneration of axons occurs in several human myelin diseases, however the molecular mechanisms of axon-glia communication maintaining axon integrity are poorl...

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Main Authors: Carsten Frühbeis, Dominik Fröhlich, Wen Ping Kuo, Jesa Amphornrat, Sebastian Thilemann, Aiman S Saab, Frank Kirchhoff, Wiebke Möbius, Sandra Goebbels, Klaus-Armin Nave, Anja Schneider, Mikael Simons, Matthias Klugmann, Jacqueline Trotter, Eva-Maria Krämer-Albers
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
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Online Access:https://doaj.org/article/f195507aa8304bdba87e81a5638558aa
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