The EMT activator ZEB1 accelerates endosomal trafficking to establish a polarity axis in lung adenocarcinoma cells

The EMT activator ZEB1 accelerates endosomal trafficking to establish a polarity axis in lung adenocarcinoma cells

The way in which metastatic tumour cells control endocytic vesicular trafficking networks to establish a front-rear polarity axis that facilitates motility remains unclear. Here, the authors show that the EMT activator ZEB1 influences vesicular trafficking dynamics to execute cell polarity change.

Guardado en:
Detalles Bibliográficos
Autores principales: Priyam Banerjee, Guan-Yu Xiao, Xiaochao Tan, Veronica J. Zheng, Lei Shi, Maria Neus Bota Rabassedas, Hou-fu Guo, Xin Liu, Jiang Yu, Lixia Diao, Jing Wang, William K. Russell, Jason Roszik, Chad J. Creighton, Jonathan M. Kurie
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/f1d2c3cc69384dc7bdd8b00a1be1cda5
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:f1d2c3cc69384dc7bdd8b00a1be1cda5
record_format dspace
spelling oai:doaj.org-article:f1d2c3cc69384dc7bdd8b00a1be1cda52021-11-08T11:12:56ZThe EMT activator ZEB1 accelerates endosomal trafficking to establish a polarity axis in lung adenocarcinoma cells10.1038/s41467-021-26677-y2041-1723https://doaj.org/article/f1d2c3cc69384dc7bdd8b00a1be1cda52021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26677-yhttps://doaj.org/toc/2041-1723The way in which metastatic tumour cells control endocytic vesicular trafficking networks to establish a front-rear polarity axis that facilitates motility remains unclear. Here, the authors show that the EMT activator ZEB1 influences vesicular trafficking dynamics to execute cell polarity change.Priyam BanerjeeGuan-Yu XiaoXiaochao TanVeronica J. ZhengLei ShiMaria Neus Bota RabassedasHou-fu GuoXin LiuJiang YuLixia DiaoJing WangWilliam K. RussellJason RoszikChad J. CreightonJonathan M. KurieNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Priyam Banerjee
Guan-Yu Xiao
Xiaochao Tan
Veronica J. Zheng
Lei Shi
Maria Neus Bota Rabassedas
Hou-fu Guo
Xin Liu
Jiang Yu
Lixia Diao
Jing Wang
William K. Russell
Jason Roszik
Chad J. Creighton
Jonathan M. Kurie
The EMT activator ZEB1 accelerates endosomal trafficking to establish a polarity axis in lung adenocarcinoma cells
description The way in which metastatic tumour cells control endocytic vesicular trafficking networks to establish a front-rear polarity axis that facilitates motility remains unclear. Here, the authors show that the EMT activator ZEB1 influences vesicular trafficking dynamics to execute cell polarity change.
format article
author Priyam Banerjee
Guan-Yu Xiao
Xiaochao Tan
Veronica J. Zheng
Lei Shi
Maria Neus Bota Rabassedas
Hou-fu Guo
Xin Liu
Jiang Yu
Lixia Diao
Jing Wang
William K. Russell
Jason Roszik
Chad J. Creighton
Jonathan M. Kurie
author_facet Priyam Banerjee
Guan-Yu Xiao
Xiaochao Tan
Veronica J. Zheng
Lei Shi
Maria Neus Bota Rabassedas
Hou-fu Guo
Xin Liu
Jiang Yu
Lixia Diao
Jing Wang
William K. Russell
Jason Roszik
Chad J. Creighton
Jonathan M. Kurie
author_sort Priyam Banerjee
title The EMT activator ZEB1 accelerates endosomal trafficking to establish a polarity axis in lung adenocarcinoma cells
title_short The EMT activator ZEB1 accelerates endosomal trafficking to establish a polarity axis in lung adenocarcinoma cells
title_full The EMT activator ZEB1 accelerates endosomal trafficking to establish a polarity axis in lung adenocarcinoma cells
title_fullStr The EMT activator ZEB1 accelerates endosomal trafficking to establish a polarity axis in lung adenocarcinoma cells
title_full_unstemmed The EMT activator ZEB1 accelerates endosomal trafficking to establish a polarity axis in lung adenocarcinoma cells
title_sort emt activator zeb1 accelerates endosomal trafficking to establish a polarity axis in lung adenocarcinoma cells
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/f1d2c3cc69384dc7bdd8b00a1be1cda5
work_keys_str_mv AT priyambanerjee theemtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT guanyuxiao theemtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT xiaochaotan theemtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT veronicajzheng theemtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT leishi theemtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT marianeusbotarabassedas theemtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT houfuguo theemtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT xinliu theemtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT jiangyu theemtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT lixiadiao theemtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT jingwang theemtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT williamkrussell theemtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT jasonroszik theemtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT chadjcreighton theemtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT jonathanmkurie theemtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT priyambanerjee emtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT guanyuxiao emtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT xiaochaotan emtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT veronicajzheng emtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT leishi emtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT marianeusbotarabassedas emtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT houfuguo emtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT xinliu emtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT jiangyu emtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT lixiadiao emtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT jingwang emtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT williamkrussell emtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT jasonroszik emtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT chadjcreighton emtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
AT jonathanmkurie emtactivatorzeb1acceleratesendosomaltraffickingtoestablishapolarityaxisinlungadenocarcinomacells
_version_ 1718442390128164864

Ejemplares similares