Extreme intratumour heterogeneity and driver evolution in mismatch repair deficient gastro-oesophageal cancer

Tumours that are deficient in mismatch-repair genes should, in theory, have higher evolvability. Here, the authors explore this theory in gastro-oesophageal tumours.

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Autores principales: Katharina von Loga, Andrew Woolston, Marco Punta, Louise J. Barber, Beatrice Griffiths, Maria Semiannikova, Georgia Spain, Benjamin Challoner, Kerry Fenwick, Ronald Simon, Andreas Marx, Guido Sauter, Stefano Lise, Nik Matthews, Marco Gerlinger
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/f202e0a95a5045ca81301d8ebb687ecf
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