Increased proteasomal activity supports photoreceptor survival in inherited retinal degeneration

Proteasomal overload can be found in a broad spectrum of mouse models of retinal degeneration. Here the authors find that overexpressing the PA28α subunit of the 11S proteasome cap increased the number of surviving functional photoreceptor cells in a mouse model of retinal degeneration bearing the P...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ekaterina S. Lobanova, Stella Finkelstein, Jing Li, Amanda M. Travis, Ying Hao, Mikael Klingeborn, Nikolai P. Skiba, Raymond J. Deshaies, Vadim Y. Arshavsky
Format: article
Langue:EN
Publié: Nature Portfolio 2018
Sujets:
Q
Accès en ligne:https://doaj.org/article/f205dd40283c431b8415d04bab375e77
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!