Parathyroid hormone receptor signalling in osterix-expressing mesenchymal progenitors is essential for tooth root formation

How the parathyroid hormone-related protein receptor (PPR) and its ligand act in root formation and tooth eruption is unclear. Here, the authors identify osterix-expressing dental mesenchymal cells as progenitors for root formation and that PPR signalling mediates their differentiation and tooth eru...

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Auteurs principaux:	Wanida Ono, Naoko Sakagami, Shigeki Nishimori, Noriaki Ono, Henry M. Kronenberg
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2016
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/f20889b00ffa4b2783a3e0e8079d534f
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id	oai:doaj.org-article:f20889b00ffa4b2783a3e0e8079d534f
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spelling	oai:doaj.org-article:f20889b00ffa4b2783a3e0e8079d534f2021-12-02T15:34:10ZParathyroid hormone receptor signalling in osterix-expressing mesenchymal progenitors is essential for tooth root formation10.1038/ncomms112772041-1723https://doaj.org/article/f20889b00ffa4b2783a3e0e8079d534f2016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11277https://doaj.org/toc/2041-1723How the parathyroid hormone-related protein receptor (PPR) and its ligand act in root formation and tooth eruption is unclear. Here, the authors identify osterix-expressing dental mesenchymal cells as progenitors for root formation and that PPR signalling mediates their differentiation and tooth eruption.Wanida OnoNaoko SakagamiShigeki NishimoriNoriaki OnoHenry M. KronenbergNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Wanida Ono Naoko Sakagami Shigeki Nishimori Noriaki Ono Henry M. Kronenberg Parathyroid hormone receptor signalling in osterix-expressing mesenchymal progenitors is essential for tooth root formation
description	How the parathyroid hormone-related protein receptor (PPR) and its ligand act in root formation and tooth eruption is unclear. Here, the authors identify osterix-expressing dental mesenchymal cells as progenitors for root formation and that PPR signalling mediates their differentiation and tooth eruption.
format	article
author	Wanida Ono Naoko Sakagami Shigeki Nishimori Noriaki Ono Henry M. Kronenberg
author_facet	Wanida Ono Naoko Sakagami Shigeki Nishimori Noriaki Ono Henry M. Kronenberg
author_sort	Wanida Ono
title	Parathyroid hormone receptor signalling in osterix-expressing mesenchymal progenitors is essential for tooth root formation
title_short	Parathyroid hormone receptor signalling in osterix-expressing mesenchymal progenitors is essential for tooth root formation
title_full	Parathyroid hormone receptor signalling in osterix-expressing mesenchymal progenitors is essential for tooth root formation
title_fullStr	Parathyroid hormone receptor signalling in osterix-expressing mesenchymal progenitors is essential for tooth root formation
title_full_unstemmed	Parathyroid hormone receptor signalling in osterix-expressing mesenchymal progenitors is essential for tooth root formation
title_sort	parathyroid hormone receptor signalling in osterix-expressing mesenchymal progenitors is essential for tooth root formation
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/f20889b00ffa4b2783a3e0e8079d534f
work_keys_str_mv	AT wanidaono parathyroidhormonereceptorsignallinginosterixexpressingmesenchymalprogenitorsisessentialfortoothrootformation AT naokosakagami parathyroidhormonereceptorsignallinginosterixexpressingmesenchymalprogenitorsisessentialfortoothrootformation AT shigekinishimori parathyroidhormonereceptorsignallinginosterixexpressingmesenchymalprogenitorsisessentialfortoothrootformation AT noriakiono parathyroidhormonereceptorsignallinginosterixexpressingmesenchymalprogenitorsisessentialfortoothrootformation AT henrymkronenberg parathyroidhormonereceptorsignallinginosterixexpressingmesenchymalprogenitorsisessentialfortoothrootformation
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Parathyroid hormone receptor signalling in osterix-expressing mesenchymal progenitors is essential for tooth root formation

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