Allosteric regulation alters carrier domain translocation in pyruvate carboxylase

Carrier domain enzymes accomplish catalysis by physically transporting intermediates long distances between remote active sites. Here the authors describe a wide range of catalytically productive translocation events during catalysis by pyruvate carboxylase and suggest a basis for its allosteric act...

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Autores principales: Yumeng Liu, Melissa M. Budelier, Katelyn Stine, Martin St. Maurice
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/f20adbd1481345a5b5a09bf6377d2d67
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