Allosteric regulation alters carrier domain translocation in pyruvate carboxylase
Carrier domain enzymes accomplish catalysis by physically transporting intermediates long distances between remote active sites. Here the authors describe a wide range of catalytically productive translocation events during catalysis by pyruvate carboxylase and suggest a basis for its allosteric act...
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Autores principales: | Yumeng Liu, Melissa M. Budelier, Katelyn Stine, Martin St. Maurice |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/f20adbd1481345a5b5a09bf6377d2d67 |
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