Positive and strongly relaxed purifying selection drive the evolution of repeats in proteins
Protein repeats may be considered a paradox, being evolutionarily conserved yet also hotspots of protein evolution associated with innovation. Here, the authors use a novel method to show that new repeats undergo rapid divergence within species, but are then fixed and conserved between species.
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Main Authors: | Erez Persi, Yuri I. Wolf, Eugene V Koonin |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2016
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Online Access: | https://doaj.org/article/f21094ba5e1f44e5a9b02459431657e9 |
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