NCK-dependent pericyte migration promotes pathological neovascularization in ischemic retinopathy

Pericytes are perivascular cells that regulate blood vessel formation and function. Here Dubrac et al. show that pericyte recruitment contributes to pathological neovascularisation in a mouse model of ischemic retinopathy, and that this depends on the regulation of PDGF-B signaling by NCK adaptor pr...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Alexandre Dubrac, Steffen E. Künzel, Sandrine H. Künzel, Jinyu Li, Rachana Radhamani Chandran, Kathleen Martin, Daniel M. Greif, Ralf H. Adams, Anne Eichmann
Format: article
Langue:EN
Publié: Nature Portfolio 2018
Sujets:
Q
Accès en ligne:https://doaj.org/article/f212c5aa389b4f57a14e393ebd8caa17
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!