Two-stage, in silico deconvolution of the lymphocyte compartment of the peripheral whole blood transcriptome in the context of acute kidney allograft rejection.

Acute rejection is a major complication of solid organ transplantation that prevents the long-term assimilation of the allograft. Various populations of lymphocytes are principal mediators of this process, infiltrating graft tissues and driving cell-mediated cytotoxicity. Understanding the lymphocyt...

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Autores principales: Casey P Shannon, Robert Balshaw, Raymond T Ng, Janet E Wilson-McManus, Paul Keown, Robert McMaster, Bruce M McManus, David Landsberg, Nicole M Isbel, Greg Knoll, Scott J Tebbutt
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/f2273797953747e9bc9dbc55318bda33
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