Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids

Brain organoids are important tools to study early development and disease but little is known of their network activity and plasticity. Here the authors generate iPSC-derived neuronal organoids that display early network formation and maturation with evidence for a GABA polarity switch and long-ter...

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Autores principales: Maria-Patapia Zafeiriou, Guobin Bao, James Hudson, Rashi Halder, Alica Blenkle, Marie-Kristin Schreiber, Andre Fischer, Detlev Schild, Wolfram-Hubertus Zimmermann
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/f2273b0bcbe64fb79978e872f203e52e
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