Excessive early-life dietary exposure: a potential source of elevated brain iron and a risk factor for Parkinson’s disease

Abstract Iron accumulates gradually in the ageing brain. In Parkinson’s disease, iron deposition within the substantia nigra is further increased, contributing to a heightened pro-oxidant environment in dopaminergic neurons. We hypothesise that individuals in high-income countries, where cereals and...

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Autores principales: Dominic J Hare, Bárbara Rita Cardoso, Erika P Raven, Kay L Double, David I Finkelstein, Ewa A Szymlek-Gay, Beverley-Ann Biggs
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/f22c5328fdf74dc0b1ae3c8bb9fca3a3
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