Cutaneous pigmentation modulates skin sensitivity via tyrosinase-dependent dopaminergic signalling

Abstract We propose a new mechanism of sensory modulation through cutaneous dopaminergic signalling. We hypothesize that dopaminergic signalling contributes to differential cutaneous sensitivity in darker versus lighter pigmented humans and mouse strains. We show that thermal and mechanical cutaneou...

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Autores principales: Kentaro Ono, Chi T. Viet, Yi Ye, Dongmin Dang, Suzuro Hitomi, Takashi Toyono, Kiyotoshi Inenaga, John C. Dolan, Brian L. Schmidt
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/f252b43606194cc794164521730b225d
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