Identification of Risk Loci for Radiotoxicity in Prostate Cancer by Comprehensive Genotyping of <i>TGFB1</i> and <i>TGFBR1</i>

Identification of Risk Loci for Radiotoxicity in Prostate Cancer by Comprehensive Genotyping of <i>TGFB1</i> and <i>TGFBR1</i>

Genetic variability in transforming growth factor beta pathway (<i>TGFB</i>) was suggested to affect adverse events of radiotherapy. We investigated comprehensive variability in <i>TGFB1</i> (gene coding for TGFβ1 ligand) and <i>TGFBR1</i> (TGFβ receptor-1) in rel...

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Autores principales: Manuel Guhlich, Laura Hubert, Caroline Patricia Nadine Mergler, Margret Rave-Fraenk, Leif Hendrik Dröge, Martin Leu, Heinz Schmidberger, Stefan Rieken, Andrea Hille, Markus Anton Schirmer
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
radiotherapy
side effects
toxicity
prostate cancer
biomarkers
TGFB
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Acceso en línea:https://doaj.org/article/f25ac930b2264c5e89db1b4aecb2d0ea
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https://doaj.org/article/f25ac930b2264c5e89db1b4aecb2d0ea

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