Knockout of Epstein-Barr Virus BPLF1 Retards B-Cell Transformation and Lymphoma Formation in Humanized Mice

ABSTRACT BPLF1 of Epstein-Barr virus (EBV) is classified as a late lytic cycle protein but is also found in the viral tegument, suggesting its potential involvement at both initial and late stages of viral infection. BPLF1 possesses both deubiquitinating and deneddylating activity located in its N-t...

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Autores principales: Christopher B. Whitehurst, Guangming Li, Stephanie A. Montgomery, Nathan D. Montgomery, Lishan Su, Joseph S. Pagano
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2015
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Acceso en línea:https://doaj.org/article/f277cc142a3d4819b92d7123e1f43e0b
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