An in vivo mechanism for the reduced peripheral neurotoxicity of NK105: a paclitaxel-incorporating polymeric micellar nanoparticle formulation

An in vivo mechanism for the reduced peripheral neurotoxicity of NK105: a paclitaxel-incorporating polymeric micellar nanoparticle formulation

Iwao Nakamura, Eiji Ichimura, Rika Goda, Hitomi Hayashi, Hiroko Mashiba, Daichi Nagai, Hirofumi Yokoyama, Takeshi Onda, Akira Masuda Nanomedicine Group, Pharmaceutical Research Laboratories, Nippon Kayaku Co., Ltd., Tokyo, Japan Abstract: In our previous rodent studies, the paclitaxel (PTX)-incorp...

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Bibliographic Details
Main Authors: Nakamura I, Ichimura E, Goda R, Hayashi H, Mashiba H, Nagai D, Yokoyama H, Onda T, Masuda A
Format: article
Language:EN
Published: Dove Medical Press 2017
Subjects:
micelle
paclitaxel
peripheral neuropathy
dorsal root ganglion
vascular permeability
Medicine (General)
R5-920
Online Access:https://doaj.org/article/f28b04af07e345a1ab2cd4ba1255a3aa
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https://doaj.org/article/f28b04af07e345a1ab2cd4ba1255a3aa

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