Germline deletion of pantothenate kinases 1 and 2 reveals the key roles for CoA in postnatal metabolism.
Pantothenate kinase (PanK) phosphorylates pantothenic acid (vitamin B(5)) and controls the overall rate of coenzyme A (CoA) biosynthesis. Pank1 gene deletion in mice results in a metabolic phenotype where fatty acid oxidation and gluconeogenesis are impaired in the fasted state, leading to mild hypo...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2012
|
| Subjects: | |
| Online Access: | https://doaj.org/article/f2a5c2a86e3544c98b022770c4c6d0b4 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|