The effects of beta-cell mass and function, intercellular coupling, and islet synchrony on $${\text {Ca}}^{2+}$$ Ca 2 + dynamics
Abstract Type 2 diabetes (T2D) is a challenging metabolic disorder characterized by a substantial loss of $$\beta $$ β -cell mass and alteration of $$\beta $$ β -cell function in the islets of Langerhans, disrupting insulin secretion and glucose homeostasis. The mechanisms for deficiency in $$\beta...
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| Auteurs principaux: | , |
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| Format: | article |
| Langue: | EN |
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Nature Portfolio
2021
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| Accès en ligne: | https://doaj.org/article/f2c53237365148c787b151a405366822 |
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