3D cell sheet structure augments mesenchymal stem cell cytokine production

Abstract Mesenchymal stem cells (MSCs) secrete paracrine factors that play crucial roles during tissue regeneration. An increasing body of evidence suggests that this paracrine function is enhanced by MSC cultivation in three-dimensional (3D) tissue-like microenvironments. Toward this end, this stud...

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Bibliographic Details
Main Authors: Sophia Bou-Ghannam, Kyungsook Kim, David W. Grainger, Teruo Okano
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/f2eaceb8ac6043cdb8dc2f9fddbe681f
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