SCYN: single cell CNV profiling method using dynamic programming

Abstract Background Copy number variation is crucial in deciphering the mechanism and cure of complex disorders and cancers. The recent advancement of scDNA sequencing technology sheds light upon addressing intratumor heterogeneity, detecting rare subclones, and reconstructing tumor evolution lineag...

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Autores principales: Xikang Feng, Lingxi Chen, Yuhao Qing, Ruikang Li, Chaohui Li, Shuai Cheng Li
Formato: article
Lenguaje:EN
Publicado: BMC 2021
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Acceso en línea:https://doaj.org/article/f2edfd418f534b77b59b2c80c97fe529
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