Replication timing and epigenome remodelling are associated with the nature of chromosomal rearrangements in cancer

Replication timing and epigenome remodelling are associated with the nature of chromosomal rearrangements in cancer

The connection between DNA replication timing and changes that occur to the epigenome in cancer are still poorly understood. Here, the authors perform Repli-Seq and integrated epigenome analyses and find that genomic regions that undergo long-range epigenetic deregulation in prostate cancer also sho...

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Autores principales: Qian Du, Saul A. Bert, Nicola J. Armstrong, C. Elizabeth Caldon, Jenny Z. Song, Shalima S. Nair, Cathryn M. Gould, Phuc-Loi Luu, Timothy Peters, Amanda Khoury, Wenjia Qu, Elena Zotenko, Clare Stirzaker, Susan J. Clark
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/f30c03fec77743c982eea9100fa0daca
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https://doaj.org/article/f30c03fec77743c982eea9100fa0daca

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